If your machine can handle it, if it doesn't take your framerate too low, I highly recommend turning Glow+Blur on (in the Options) and playing fullscreen (press F11 in Windows) because it's awesome.
Though it turns out that up until today it didn't work.
I discovered this crash bug by myself, accidentally - when you have glow & blur on, and you resize the window, it would crash. Apparently that bug has been in there since the beginning of time, which means probably nobody was playing with Glow+Blur *and* fullscreen.
I thought it might be some kind of OpenGL fragmentation - maybe reallocating the buffers for the different sized window was using up memory. But no, it was me being stupid: I was deleting the same texture pointers twice.